Accumulation of essential oils in relation to root differentiation in Angelica archangelica L.

Evaluation of Antiseizure Activity of Essential Oil from Roots of Angelica archangelica Linn. in Mice

In the present study, the effect of essential oil of the root of Angelica archangelica Linn. was evaluated against electrically and chemically induced seizures. The seizures were induced in mice by maximal electroshock and pentylenetetrazol. The effect of essential oil of the root of Angelica archangelica on seizures was compared with standard anticonvulsant agents, phenytoin and diazepam. The ...

Influence of Copper and Zinc on Growth, Metal Accumulation and Chemical Composition of Essential Oils in Sweet Basil (Ocimum basilicum L.)

Background: Biosynthesis and metabolism of phytochemicals in medicinal and aromatic plants are vigorously affected by different abiotic elicitors including chemicals. Objective: This experiment was designed to investigate the effects of three levels of copper sulfate (Cu: 0, 5, 25 mg kg-1) and zinc sulfate (Zn: 0, 10, 50 mg kg-1) and their combinations on yield, chemical compositions of esse...

Inhibition of acetylcholinesterase by extracts and constituents from Angelica archangelica and Geranium sylvaticum.

The aim of this study was to explore the acetylcholinesterase (AChE) inhibition of several Icelandic medicinal herbs. Ethanolic extracts of Angelica archangelica seeds and the aerial parts of Geranium sylvaticum proved effective, with IC50 values of 2.20 mg/ml and 3.56 mg/ml, respectively. The activity of imperatorin and xanthotoxin from A. archangelica was measured. Xanthotoxin proved much mor...

Division of Pharmaceutical Biology Faculty of Pharmacy University of Helsinki Plant secondary metabolites in Peucedanum palustre and Angelica archangelica and their plant cell cultures

Antiproliferative effect of Angelica archangelica fruits.

The aim of this work was to study the antiproliferative effect of a tincture from fruits of Angelica archangelica and the active components using the human pancreas cancer cell line PANC-1 as a model. Significant dose-dependent antiproliferative activity was observed in the tincture with an EC50 value of 28.6 microg/ml. Strong antiproliferative activity resulted from the two most abundant furan...